Japanese Knotweed Root
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Japanese Knotweed Root
What is Japanese Knotweed?
Japanese Knotweed, also known as Polygonum cuspidatum, is a traditional botanical widely recognized as one of nature’s richest sources of resveratrol. Green Dragon Botanicals Japanese Knotweed capsules provide 500 mg of wild-harvested Japanese Knotweed root per serving, offering daily antioxidant support for immune, cardiovascular, neurocognitive, and whole-body wellness.*
How Japanese Knotweed fits into your routine
Japanese Knotweed is often used by adults looking for a natural resveratrol supplement and plant-based support for long-term wellness. This formula may be used as a daily foundation for:
- Immune support: supports healthy immune system function and resilience*
- Cardiovascular wellness: supports heart and circulatory system health*
- Antioxidant protection: helps support cellular health against oxidative stress*
- Neurocognitive support: supports healthy brain and nervous system function*
- Whole-body balance: supports overall vitality as part of a daily herbal routine*
Why resveratrol support matters
Resveratrol is a naturally occurring plant compound valued for its antioxidant properties. Antioxidants help support the body’s natural defense against oxidative stress, which can affect cellular health, immune resilience, and long-term wellness. Japanese Knotweed root is one of the most recognized herbal sources of resveratrol.*
What are the benefits of Japanese Knotweed?
- Provides 500 mg of wild-harvested Japanese Knotweed root per serving
- Natural botanical source of resveratrol
- Supports immune system health and resilience*
- Supports cardiovascular and circulatory wellness*
- Supports antioxidant protection and cellular health*
- Supports healthy neurocognitive and nervous system function*
- Made with wild-harvested Japanese Knotweed root sourced from the USA
- Gluten-free, vegetarian, and non-GMO
- Third-party tested for purity and quality
- Manufactured in the USA under GMP standards
Formulated by an experienced herbalist
Developed with practitioner-informed herbal guidance from Timothy Scott, an herbalist who studied with Stephen Harrod Buhner, author of Healing Lyme. This practitioner-informed formula is designed for adults seeking plant-based support for immune health, antioxidant protection, cardiovascular wellness, and whole-body vitality.*
Who is Japanese Knotweed typically recommended for?
Japanese Knotweed is commonly used by adults looking for a natural resveratrol supplement that supports immune health, cardiovascular wellness, antioxidant protection, and overall vitality.* It may be especially suitable for those who prefer a gluten-free, vegetarian, non-GMO herbal supplement made from wild-harvested root.
How do I take Japanese Knotweed?
Take as directed on the product label, or as recommended by your health care practitioner.
What’s inside Japanese Knotweed?
Japanese Knotweed Root
Japanese Knotweed root, also known as Polygonum cuspidatum, is a traditional botanical valued for its naturally occurring resveratrol content. Resveratrol is a plant-based antioxidant compound that helps support cellular health and the body’s natural defenses against oxidative stress.*
Each serving provides 500 mg of wild-harvested Japanese Knotweed root. This formula is designed to support immune wellness, cardiovascular health, neurocognitive function, and overall vitality as part of a daily supplement routine.*
Green Dragon Botanicals Japanese Knotweed capsules are gluten-free, vegetarian, non-GMO, third-party tested, and manufactured in the USA under GMP standards.
Frequently Asked Questions
How do I take the herbal protocol? (LB CORE / LB TONIC)
Base dose is 3 capsules, 3X/day, working up 3 capsules at a time on a weekly basis to a maximum of 12 capsules, 3-4X/day.
Suggested use:
Week 1 - 3 capsules, 3X/day
Week 2 - 6 capsules, 3X/day
Week 3 - 9 capsules, 3X/day
Week 4 - 12 capsules, 3X/day
Week 5+ - 12 capsules, 4X/day
For the liquid version of the protocol, the suggested use is ¼-1 tsp., 3-4X/day. 1 tsp. of liquid is approximately equal to 12 capsules.
Maintain maximum dose the body tolerates for at least 60 days, and depending on severity and duration of illness, the herbs can be lowered to a maintenance dose. Continue use of the herbs for 8-12 months or until symptoms are resolved. If symptoms worsen upon lowering the dose, increase. The herbs can be taken with or without food, at any time of day.
If you miss a dose or even a full week, there's no need to restart the titration schedule — just resume at your previous dose.
If there is any digestive upset (bloating, diarrhea, gas, distention, etc.) while increasing your dose, back down to a lower, more comfortable dose and titrate up again as your digestion allows.
What is the dosage for single-herb capsules (Japanese Knotweed, Cat's Claw, Andrographis)?
Week 1 - 1 capsule of each herb, 3X/day
Week 2 - 2 capsules of each, 3X/day
Week 3 - 3 capsules of each, 3X/day
Week 4 - 4 capsules of each, 3X/day
Week 5+ - 4 capsules of each, 4X/day
This schedule applies to Japanese Knotweed, Cat's Claw, and Andrographis capsules taken individually — it does not apply to MangoForte.
This is the same overall dose as the LB CORE Protocol, just measured per individual herb rather than as a pre-combined blend — taking the herbs individually doesn't lessen the amount, it's the same formula, just not combined into one capsule.
Can I take LB CORE and LB TONIC together?
Yes — use the same dose schedule as taking either one alone. You can split them by time of day (for example, LB TONIC in the morning and afternoon, LB CORE in the evening) or mix them together (for example, 2 capsules LB TONIC + 1 capsule LB CORE at the same time).
What is a Herxheimer reaction?
A Herxheimer reaction ("herx") is a temporary worsening of symptoms as the body processes die-off from the herbs — generally a sign the herbs are active, not that they're harmful.
Adding detox-supportive herbs and supplements can help ease a herx response. If your reaction is severe or isn't improving, slow down your titration and reach out to us.
What are the potential side effects of the herbs?
Digestive issues may arise with bloating, gas, diarrhea, abdominal distention, etc. and this is an indication of too high a dose. Lower the amount of herbs to where is comfortable.
Andrographis has created an allergic response in about 1% of those taking it. This manifests as a full body rash or hives when first taking it, which is then relieved when the herb is discontinued, though may take time to resolve completely.
What are the cautions/contraindications of the protocol?
Use Japanese knotweed with caution with blood thinning medications and discontinue the use of the herb 10 days prior to surgery.
The LB CORE protocol is contraindicated if pregnant or trying to get pregnant, and consult a health care practitioner if breast-feeding.
The liquid LB CORE protocol contains honey. Do not use if you are allergic to bee products. Not for use by children under 1 year of age.
Can I take this with antibiotics or other medications?
This depends on the specific medication and situation, so we recommend booking a consultation rather than relying on a general answer.
The one general interaction we can state directly: use Japanese Knotweed with caution alongside blood-thinning medications. For anything more specific, Tim's books are a good next resource, or book a consultation for guidance tailored to your situation.
What is the difference between the LB CORE and the LB TONIC?
Both protocols contain the same core herbs — Japanese Knotweed, Cat's Claw, Dandelion, and Sarsaparilla — with one difference: LB CORE contains Andrographis (anti-bacterial, anti-inflammatory), while LB TONIC has Eleuthero (immune/adrenal support) instead.
Both protocols are appropriate for chronic Lyme, have the same dosage, and can be used interchangeably — or combined (see "Can I take LB CORE and LB TONIC together?" above). The TONIC was developed as an alternative to the CORE for those who prefer a formula without Andrographis.
What is the glycerin in the tinctures derived from?
Our tinctures use organic flaxseed-derived glycerin, sourced through Five Flavors Herbs.
How does the capsule dose compare to the liquid (tincture) dose?
The capsule and liquid (tincture) versions of the same formula follow the same ramp-up schedule and are equivalent at each step — as a general guide, 1 teaspoon of liquid is approximately equal to 12 capsules.
| Week | Capsules | Liquid (tsp) |
|---|---|---|
| Week 1 | 3 capsules, 3X/day | ¼ tsp, 3X/day |
| Week 2 | 6 capsules, 3X/day | ½ tsp, 3X/day |
| Week 3 | 9 capsules, 3X/day | ¾ tsp, 3X/day |
| Week 4 | 12 capsules, 3X/day | 1 tsp, 3X/day |
| Week 5+ | 12 capsules, 4X/day | 1 tsp, 4X/day |
Capsules are alcohol-free and are generally recommended for anyone with alcohol sensitivity (such as MCAS). The liquid tincture contains grain alcohol but is absorbed more quickly — to reduce the alcohol taste and content, drops can be added to a small amount of boiling water and left to cool for about 5 minutes before taking.
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